In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. Synthetic Route of 538-58-9,
The tributylphosphine-catalyzed bis-Michael addition reaction of various kinds of alpha,beta-unsaturated carbonyl compounds with active methylenes is described. This is a convenient and rapid method for generating quaternary carbons centers and useful procedure for the synthesis of branched core and highly substituted trans cyclohexanones. All the reactions were completed in 60 min and afford the corresponding products in excellent yields.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 538-58-9. In my other articles, you can also check out more blogs about Synthetic Route of 538-58-9
Reference：
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate