The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: cis-4-Aminocyclohexane carboxylic acid( cas:3685-23-2 ) is researched.Computed Properties of C7H13NO2.Alen, Jo; De Borggraeve, Wim M.; Compernolle, Frans; Hoornaert, Georges J. published the article 《Evaluation of the β-turn-inducing properties of an analog of (amino)piperidinonecarboxylates》 about this compound( cas:3685-23-2 ) in Proceedings of ECSOC-10, International Electronic Conference on Synthetic Organic Chemistry, 10th, Nov. 1-30, 2006. Keywords: beta turn mimetic acetylamino cyclohexanecarboxamide preparation. Let’s learn more about this compound (cas:3685-23-2).
Cis-4-(Acetylamino)-N-(methyl)cyclohexanecarboxamide has been selected as all carbon ring analog of previously described 5-(amino)piperidinone-2-carboxylate systems. The potential β-turn-inducing properties of this model compound are evaluated by means of NMR anal. and mol. modeling. It was found that suitable as β-turn-inducing scaffold. Apparently, the planar lactam function in the native (amino)(oxo)piperidinecarboxylate systems is important to impose a correct conformation for β-turn induction.
If you want to learn more about this compound(cis-4-Aminocyclohexane carboxylic acid)Computed Properties of C7H13NO2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(3685-23-2).
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate