In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called TD-GC-MS investigation of the VOCs released from blood plasma of dogs with cancer, published in 2013-03-31, which mentions a compound: 616-43-3, mainly applied to VOC blood plasma dog cancer TD GC MS; TD-GC-MS; cancer markers; dog blood plasma; volatile organic compounds, Reference of 3-Methyl-1H-pyrrole.
An anal. TD-GC-MS method was developed and used for the assessment of volatile organic compounds (VOCs) released from the blood plasma of dogs with/without cancer. VOCs released from 40 samples of diseased blood and 10 control samples were compared in order to examine the difference between both sample groups that were showing qual. similar results independent from the disease’s presence. However, mild disturbances in the spectra of dogs with cancer in comparison with the control group were observed, and six peaks (tentatively identified by comparison with mass spectral library as hexanal, octanal, toluene, 2-butanone, 1-octen-3-ol and pyrrole) revealed statistically significant differences between both sample groups, thereby suggesting that these compounds are potential biomarkers that can be used for cancer diagnosis based on the blood plasma TD-GC-MS anal. Statistical comparison with the application of principal component anal. (PCA) provided accurate discrimination between the cancer and control groups, thus demonstrating stronger biochem. perturbations in blood plasma when cancer is present.
I hope my short article helps more people learn about this compound(3-Methyl-1H-pyrrole)Reference of 3-Methyl-1H-pyrrole. Apart from the compound(616-43-3), you can read my other articles to know other related compounds.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate