The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: cis-4-Aminocyclohexane carboxylic acid( cas:3685-23-2 ) is researched.SDS of cas: 3685-23-2.Karpavicius, K.; Patockiene, L.; Knunyants, I. L. published the article 《Synthesis of peptidelike derivatives of cis- and trans-4-aminocyclohexanecarboxylic acids containing sarcolysin residues》 about this compound( cas:3685-23-2 ) in Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya. Keywords: aminocyclohexanecarbonylsarcolysin; sarcolysin aminocyclohexanecarbonyl; sarcolysinamide cyclohexyl; sarcolysylaminocyclohexanecarboxylate. Let’s learn more about this compound (cas:3685-23-2).
Mixed-anhydride and dicyclohexylcarbodiimide coupling reactions of N-formysarcolysin and N-(benzyloxycarbonyl)sarcolysin with cis- and trans-4-aminocyclohexanecarboxylic acid esters and subsequent deblocking gave the cis- and trans- sarcolysylaminocyclohexanecarboxylates I (R = H, Et). Condensation of sarcolysin benzyl ester with cis- and trans-4-(benzyloxycarbonylamino)cyclohexancarboxylate and subsequent deblocking gave the cis- and trans-N-(cyclohexylcarbonyl)sarcolysins II.
This literature about this compound(3685-23-2)SDS of cas: 3685-23-2has given us a lot of inspiration, and I hope that the research on this compound(cis-4-Aminocyclohexane carboxylic acid) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate