Synthetic Route of 538-58-9, Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, new energy materials, nano-ceramics, nano-hybrid composite materials, preparation and modification of special coatings. 538-58-9, Name is 1,5-Diphenylpenta-1,4-dien-3-one,introducing its new discovery.
Antimicrobial Activity of Monoketone Curcuminoids Against Cariogenic Bacteria
We evaluated the antimicrobial activity of 25 monoketone curcuminoids (MKCs) against a representative panel of cariogenic bacteria in terms of their minimum inhibitory concentration (MIC) values. Curcumin A (10) displayed promising activity against Streptococcus mutans (MIC = 50 mug/ml) and Streptococcus mitis (MIC = 50 mug/ml) as well as moderate activity against S. sanguinis (MIC = 100 mug/ml), Lactobacillus casei (MIC = 100 mug/ml), and Streptococcus salivarius (MIC = 200 mug/ml). Results indicated higher activity of compound 10 than that of its bis-beta-diketone analog. Additionally, compounds 3a (1,5-bis(4-methylphenyl)pentan-3-one) and 7b (1,5-bis(4-bromophenyl)pentan-3-ol) were moderately active against S. mitis (MIC = 100 mug/ml) and S. salivarus (MIC = 200 mug/ml).
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms.In my other articles, you can also check out more blogs about538-58-9.Synthetic Route of 538-58-9
Reference：
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate