Segal, Menahem; Sims, Kenneth; Maggiora, Linda; Smissman, Edward published an article about the compound: cis-4-Aminocyclohexane carboxylic acid( cas:3685-23-2,SMILESS:N[C@H]1CC[C@H](CC1)C(O)=O ).Application of 3685-23-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:3685-23-2) through the article.
The response of hippocampal neurons to iontophoretic application of aminocyclohexanecarboxylic acid analogs of GABA in the presence of 0.5M acetylcholine or 15mM bicuculline showed that a precise spatial separation of the NH2 and CO2H groups was necessary to mimic the physiol. effects of GABA.
Although many compounds look similar to this compound(3685-23-2)Application of 3685-23-2, numerous studies have shown that this compound(SMILES:N[C@H]1CC[C@H](CC1)C(O)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate