HPLC of Formula: 3685-23-2. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Renin inhibitory pentols showing improved enteral bioavailability. Author is Kleemann, Heinz Werner; Heitsch, Holger; Henning, Rainer; Kramer, Werner; Kocher, Walter; Lerch, Ulrich; Linz, Wolfgang; Nickel, Wolf Ulrich; Ruppert, Dieter.
Aminopentols derived from L-(+)-glucose and D-(+)-mannose were prepared and tested for renin-inhibiting activity as well as bioavailability. Incorporation of a C-terminal pentahydroxy functionality led to potent, low mol. weight hydrophilic renin inhibitors lacking the p1′ side chain. I was transported across rabbit intestinal brush border membrane vesicles and yielded a hypotensive effect in sodium-depleted rhesus monkeys which lasted for 90 min when dosed at 2 mg/kg, intraduodenally.
Different reactions of this compound(cis-4-Aminocyclohexane carboxylic acid)HPLC of Formula: 3685-23-2 require different conditions, so the reaction conditions are very important.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate