Discovery of 3685-23-2

The article 《Renin inhibitory pentols showing improved enteral bioavailability》 also mentions many details about this compound(3685-23-2)Application of 3685-23-2, you can pay attention to it, because details determine success or failure

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Renin inhibitory pentols showing improved enteral bioavailability, published in 1992-02-07, which mentions a compound: 3685-23-2, Name is cis-4-Aminocyclohexane carboxylic acid, Molecular C7H13NO2, Application of 3685-23-2.

Aminopentols derived from L-(+)-glucose and D-(+)-mannose were prepared and tested for renin-inhibiting activity as well as bioavailability. Incorporation of a C-terminal pentahydroxy functionality led to potent, low mol. weight hydrophilic renin inhibitors lacking the p1′ side chain. I was transported across rabbit intestinal brush border membrane vesicles and yielded a hypotensive effect in sodium-depleted rhesus monkeys which lasted for 90 min when dosed at 2 mg/kg, intraduodenally.

The article 《Renin inhibitory pentols showing improved enteral bioavailability》 also mentions many details about this compound(3685-23-2)Application of 3685-23-2, you can pay attention to it, because details determine success or failure

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate