Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 616-43-3, is researched, SMILESS is CC1=CNC=C1, Molecular C5H7NJournal, International Journal of Chemical Sciences called Synthesis and characterization of N-Mannich bases with pyrimethamine for antimicrobial activities, Author is Senthilraja, M.; Thangadhurai, S. Anand, the main research direction is bactericide fungicide Mannich isatin pyrimethamine Schiff base; antibacterial isatin pyrimethamine Mannich Schiff base.Recommanded Product: 616-43-3.
Schiff bases of isatin with pyrimethamine and its N-Mannich bases were synthesized. Antimicrobial evaluation was done by agar dilution method against 10 pathogenic bacteria and 4 pathogenic fungi. The new derivatives exhibited higher potency compared to the standard drugs against all organisms (against all bacteria). All the compounds exhibited antifungal activity.
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Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate