Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Synthesis and biological study of bis(2-chloroethyl) sulfides containing carboxylic groups. 3. Cyclohexylamides of 3(or 4)-chloro-4(or 3)-[(2-chloroethyl)thio]butanoic acids.Computed Properties of C7H13NO2.
Cyclohexylamides Cl(CH2)2SCH(CH2Cl)CH2CONHC6H10R and Cl(CH2)2SCH2CHClCH2CONHC6H10R-4 (C6H10 = cyclohexane moiety, R = H, cis- or trans-CO2H, or -CH2CO2H, cis-β-substituted-DL-Ac-β-Ala-OH) were prepared by addition reaction of butenamides with Cl(CH2)2SCl. The biol. assay shows that the products are less toxic than analogous acids or phenylamides, whereas their antitumor effect remains high.
From this literature《Synthesis and biological study of bis(2-chloroethyl) sulfides containing carboxylic groups. 3. Cyclohexylamides of 3(or 4)-chloro-4(or 3)-[(2-chloroethyl)thio]butanoic acids》,we know some information about this compound(3685-23-2)Computed Properties of C7H13NO2, but this is not all information, there are many literatures related to this compound(3685-23-2).
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate