538-58-9,A common heterocyclic compound, 538-58-9,1,5-Diphenylpenta-1,4-dien-3-one, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: Method A: A mixture of appropriate derivatives of both 1,3-diaryl-2-propen-1-ones (1.0 equiv.) and aryl hydrazine (1.1 equiv.) was taken in a 100mL round-bottomed flask in 95% ethanol (25mL). Addition of a drop of H2SO4 initiated the precipitation. The reaction mixture was refluxed for 3 to 5h and cooled to room temperature to form precipitate in most of the cases. The residue was filtered, washed with water and dried under vacuum. In some cases where precipitate was not observed after cooling to room temperature, water was added to obtain precipitate.
The chemical industry reduces the impact on the environment during synthesis, 538-58-9,1,5-Diphenylpenta-1,4-dien-3-one,I believe this compound will play a more active role in future production and life.
Reference£º
Article; Ananthnag, Guddekoppa S.; Adhikari, Adithya; Balakrishna, Maravanji S.; Catalysis Communications; vol. 43; (2014); p. 240 – 243;,
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate