The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5,6-Dichloropyrazine-2,3-dicarbonitrile( cas:56413-95-7 ) is researched.COA of Formula: C6Cl2N4.Kopecky, Kamil; Novakova, Veronika; Miletin, Miroslav; Kucera, Radim; Zimcik, Petr published the article 《Synthesis of new azaphthalocyanine dark quencher and evaluation of its quenching efficiency with different fluorophores》 about this compound( cas:56413-95-7 ) in Tetrahedron. Keywords: dark quencher azaphthalocyanine preparation quenching fluorophore; azide alkyne dipolar cycloaddition azaphthalocyanine preparation. Let’s learn more about this compound (cas:56413-95-7).
A new unsym. zinc azaphthalocyanine (AzaPc) was synthesized using statistical condensation of two precursors. Postsynthetic modifications led to incorporation of the azide group that efficiently underwent Cu(I)-catalyzed azide/alkyne 1,3-dipolar cycloaddition with terminal alkyne on a solid phase. The modified solid phase was then used for synthesis of oligodeoxyribonucleotides labeled with AzaPc. DNA hybridization assays confirmed high quenching efficiency (QE>96%) of zinc AzaPc quencher with six different fluorophores ranging in emission maxima from 517 nm to 701 nm (FAM, HEX, Cy3, Cy3.5, Cy5, and Cy5.5).
There are many compounds similar to this compound(56413-95-7)COA of Formula: C6Cl2N4. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate