Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 3685-23-2, is researched, SMILESS is N[C@H]1CC[C@H](CC1)C(O)=O, Molecular C7H13NO2Journal, Article, Bioorganic & Medicinal Chemistry Letters called Conformationally restricted indolopiperidine derivatives as potent CCR2B receptor antagonists, Author is Witherington, J.; Bordas, V.; Cooper, D. G.; Forbes, I. T.; Gribble, A. D.; Ife, R. J.; Berkhout, T.; Gohil, J.; Groot, P. H. E., the main research direction is indolylazabicyclooctylmethylcyclohexyl dichlorocinnamamide preparation CCR2B receptor antagonist.HPLC of Formula: 3685-23-2.
The preparation and biol. evaluation of a series of indolopiperidine CCR2B receptor antagonists possessing a conformationally restricted C-5 linker chain in combination with a restricted piperidine ring are described. Compared to the parent compound, the analog I shows a dramatic improvement in selectivity against a range of 5-HT and dopaminergic receptors.
Compound(3685-23-2)HPLC of Formula: 3685-23-2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-4-Aminocyclohexane carboxylic acid), if you are interested, you can check out my other related articles.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate