So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Palaima, A.; Poskiene, R.; Karpavicius, K.; Kil’disheva, O. V.; Knunyants, I. L. researched the compound: cis-4-Aminocyclohexane carboxylic acid( cas:3685-23-2 ).Synthetic Route of C7H13NO2.They published the article 《The cis-3- and trans-4-aminocyclohexanecarboxylic acids and their esters》 about this compound( cas:3685-23-2 ) in Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya. Keywords: cyclohexane carboxylate amino isomer; aminocyclohexanecarboxylate. We’ll tell you more about this compound (cas:3685-23-2).
Mixtures of cis- and trans-3-(I) and 4-aminocyclohexanecarboxylic acid (II) were obtained by hydrogenation of the corresponding aminobenzoic acids. Trans-II and cis-I were obtained in 85 and 83% yield, resp., by separation of the mixture on a KU-2 cation exchanger. Cis-II was isomerized to 90% trans-II in the presence of 2% NaOH and Ni/Re catalyst. The Et and Me esters of the title compounds were also obtained.
There is still a lot of research devoted to this compound(SMILES：N[C@H]1CC[C@H](CC1)C(O)=O)Synthetic Route of C7H13NO2, and with the development of science, more effects of this compound(3685-23-2) can be discovered.
Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate