This type of reactivity has quickly become one of the cornerstones of modern catalysis .In a patent, category: chiral-oxygen-ligands, name is (S)-Propane-1,2-diol, belongs to chiral-oxygen-ligands compound, introducing its new discovery. category: chiral-oxygen-ligands
PROCESS FOR THE PRODUCTION OF ALKANEDIOL DERIVATIVES
The present invention provides a process for producing an alkanediol derivative represented by the general formula (II) from an ester compound represented by the general formula (I), safely without giving rise to racemization.The present invention lies in a process for producing an alcohol derivative represented by the following general formula (II):(wherein R2and R3are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; X is a hydrogen atom or a protecting group for hydroxyl group; and n is 0 or 1), which process comprises reducing an ester compound represented by the following general formula (I):(wherein R1is an alkyl group having 1 to 4 carbon atoms; and R2, R3, X and n have the same definitions as given above) with sodium borohydride in a mixed solvent of at least one kind of solvent selected from the group consisting of aromatic hydrocarbons, aliphatic hydrocarbons and alicyclic hydrocarbons and a primary alcohol.
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Reference：
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate