A new application about (S)-Butane-1,3-diol

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Synthetic Route of 24621-61-2, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Synthetic Route of 24621-61-2

Synthetic Route of 24621-61-2, Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about Synthetic Route of 24621-61-2, Name is (S)-Butane-1,3-diol

Efficient synthesis of the ketone body ester (R)-3-hydroxybutyryl-(R)-3-hydroxybutyrate and its (S,S) enantiomer

The ketone body ester (R)-3-hydroxybutyryl-(R)-3-hydroxybutyrate and its (S,S) enantiomer were prepared in a short, operationally simple synthetic sequence from racemic beta-butyrolactone. Enantioselective hydrolysis of beta-butyrolactone with immobilized Candida antarctica lipase-B (CAL-B) results in (R)-beta-butyrolactone and (S)-beta-hydroxybutyric acid, which are easily converted to (R) or (S)-ethyl-3-hydroxybutyrate and reduced to (R) or (S)-1,3 butanediol. Either enantiomer of ethyl-3-hydroxybutyrate and 1,3 butanediol are then coupled, again using CAL-B, to produce the ketone body ester product. This is an efficient, scalable, atom-economic, chromatography-free, and low cost synthetic method to produce the ketone body esters.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Synthetic Route of 24621-61-2, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Synthetic Route of 24621-61-2

Reference£º
Synthesis and Crystal Structure of a Chiral?C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur¨Cnitrogen¨Coxygen ligand derived from aminothiourea and sodium?D-camphor-¦Â-sulfonate