Month: May 2024

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5,6-Dichloropyrazine-2,3-dicarbonitrile(SMILESS: N#CC1=NC(Cl)=C(Cl)N=C1C#N,cas:56413-95-7) is researched.Recommanded Product: 3-Methyl-1H-pyrrole. The article 《Dually directional glycosylated phthalocyanines as extracellular red-emitting fluorescent probes》 in relation to this compound, is published in Dalton Transactions. Let’s take a look at the latest research on this compound (cas:56413-95-7).

The development of new non-aggregated phthalocyanines bearing multivalent saccharide moieties on their macrocyclic rims is of great interest. Many characteristics, including water-solubility, non-toxicity and others, can be feasibly obtained by these amphiphiles which can be considered as a key solution for demonstrating highly efficient photoactive materials in water. Herein, a family of five newly prepared dually directional Zn(II) containing phthalocyanines (PcG1-4) and azaphthalocyanine (AzaPcG1) glycoconjugates is described. The unique spatial arrangement of the glucoside units based on peripherally hexadeca-(PcG1) and nonperipherally octa-(PcG4) macrocycles provides a fully monomeric behavior along with a high fluorescence (ΦF ~0.21) in aqueous solution These amphiphiles were characterized by low toxicity, and an extremely low cellular uptake was obtained due to the highly polar nature of the glucoside substituents. Accordingly, their potential as suitable photoactive chromophores for red-emitting extracellular fluorescent probes has been confirmed upon the evaluation of paracellular transport using a layer of MDCKII cells with the permeability coefficient fully comparable with an established evaluator of the integrity of the monolayer.

The article 《Dually directional glycosylated phthalocyanines as extracellular red-emitting fluorescent probes》 also mentions many details about this compound(56413-95-7)Computed Properties of C6Cl2N4, you can pay attention to it or contacet with the author([email protected]; [email protected]) to get more information.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Name: cis-4-Aminocyclohexane carboxylic acid. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Synthesis and opioid activity of dynorphin A-(1-13)NH2 analogs containing cis- and trans-4-aminocyclohexanecarboxylic acid. Author is Snyder, Kristin R.; Murray, Thomas F.; DeLander, Gary E.; Aldrich, Jane V..

4-Aminocyclohexanecarboxylic acid (I) was synthesized by catalytic hydrogenation of p-aminobenzoic acid, and the cis and trans isomers were separated by fractional recrystallization Analogs of dynorphin A(1-13)amide containing cis- and trans-I were prepared by solid-phase peptide synthesis using the 9-fluorenylmethoxycarbonyl (Fmoc) chem. protocol. Results from radioligand binding assays indicated that the peptides have modest affinity for κ opioid receptors and modest κ-receptor selectivity. These analogs containing cis- and trans-I are the first reported dynorphin A analogs constrained in the message sequence that are selective for κ receptors. The analog containing cis-I showed very weak opioid activity in the guinea pig ileum.

Different reactions of this compound(cis-4-Aminocyclohexane carboxylic acid)Name: cis-4-Aminocyclohexane carboxylic acid require different conditions, so the reaction conditions are very important.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate

Synthetic Route of C7H13NO2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: cis-4-Aminocyclohexane carboxylic acid, is researched, Molecular C7H13NO2, CAS is 3685-23-2, about Synthesis of peptides containing cis- or trans-3- or 4-aminocyclohexanecarboxylic acid residues.

Et tert-butoxycarbonylphenylalanyl-trans- and -cis-4-aminocyclohexanecarboxylates were prepared by coupling the N-hydroxysuccinimido ester of tert-butoxycarbonylphenylalanine with a mixture of isomers of Et 4-aminocyclohexanecarboxylate. Treatment of the hydroxysuccinimido esters of tert-butoxycarbonylphenylalanyl-trans-4- and -cis-3-aminocyclohexanecarboxylic acids with S-benzylcysteine Me ester gave tert-butoxycarbonylphenylalanyl-trans-4- and -cis-3-aminocyclohexylcarbonyl-S-benzylcysteine Me ester.

Different reactions of this compound(cis-4-Aminocyclohexane carboxylic acid)Synthetic Route of C7H13NO2 require different conditions, so the reaction conditions are very important.

Reference:
Synthesis and Crystal Structure of a Chiral C3-Symmetric Oxygen Tripodal Ligand and Its Applications to Asymmetric Catalysis,
Chiral lanthanide(III) complexes of sulphur–nitrogen–oxygen ligand derived from aminothiourea and sodium D-camphor-β-sulfonate